Original Research Article
Year: 2019 | Month: December | Volume: 9 | Issue: 12 | Pages: 305-309
Gastric Cancer- Clinical Profile from a Single Center Experience in South India
Giri GV, Lakshmaiah. KCGovind Babu.K, Linu Abraham Jacob, Suresh Babu M.C, Lokanatha D, Suparna
Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
Corresponding Author: Giri GV
ABSTRACT
Gastric cancer is one of the major causes of mortality in South East Asian countries with India being no exception. We carried out this retrospective observational study to highlight the clinical profile of gastric cancer in south India as there is sporadic data regarding the same. This study was carried out at a tertiary care oncology center in South India and 52 patients of gastric adenocarcinoma confirmed histopathologically and by immunohistochemistry were studied from January 2012 to December 2014. The male to female ratio was 2.25:1. The main presenting symptoms were pain abdomen and loss of appetite. The stage wise distribution of the cohort was as follows –2 patients of stage 1, 12 patients of stage 2 , 3 in stage 3 and 8 patients of metastatic disease( stage 4) . There were 21 patients who had locally advanced cancer at presentation. Histologically, all were adenocarcinoma, with 6 being signet ring and 7 poorly differentiated carcinoma. The treatment procured was as follows- 17patients were operated upon and 36 patients received chemotherapy. The regimens administered were as follows - ECF in 24 patients, Mc Donald’s regime in 1 patient, DCF in 4 patients, Cisplatin +5 Fluorouracil+ Leucovorin in 3 patients, paclitaxel+carboplatin in 1 patient, FOLFOX in 1 and docetaxel +cisplatin in 2 patients. 5 patients didn’t complete evaluation and received no treatment. Further studies are required to analyse the outcome of this dreaded malignancy in India.
Key words: Gastric cancer, clinical profile, gastric adenocarcinoma, south India.