Original Research Article
Year: 2017 | Month: May | Volume: 7 | Issue: 5 | Pages: 47-51
Efficacy of Vacuum-Assisted Closure Therapy versus Conventional Povidone Iodine Dressing in the Management of Diabetic Foot Ulcers: A Randomized Control Trial
Dr. B.M. Kajagar, Dr. Kunal Joshi
Department of Surgery, KLE’s University Jawaharlal Nehru Medical College, Belgavi 590010,
Corresponding Author: Dr. B.M. Kajagar
ABSTRACT
Objective: To equate the effectiveness of vacuum-assisted closure therapy (VACT) with conventional povidone iodine dressing (CTPID)in the management of diabetic foot ulcer (DFU).
Methods: It was a 14-day study in which a total of 60 patients were divided into two equal groups (n = 30) using computer-generated random numbers. Group A and group B received VACT and CTPID treatment for DFU, respectively. A sub atmospheric pressure of 100–125 mmHg was applied to the wound in VACT group and povidone iodine-soaked gauze was used for dressing in CTPID group. The wounds were assessed on day 0, 5 and 14 of the treatment for the mean area of ulcer. Culture sensitivity test for bacterial growth was performed on day 0 and 14 to determine the infection status by disc diffusion method.
Result: At the end of the study (day 14),mean surface area of the ulcer treated with VACT and CTPID was reduced from 11.21cm2 to 8.6cm2 and 12.24cm2 to 11.30 cm2, respectively (p = 0.029). Two patients of group A and eight patients of group B showed positive growth for gram-positive cocci such as Staphylococcus aureus, and gram-negative organisms such as E.coli, Proteus, Klebsiella, Pseudomonas and Enterococcus on day 14 of repeat culture (p = 0.038).
Interpretation: VACT was found to be more effective in treating DFU with respect to healing rate and time when compared to the conventional povidone iodine dressing.
Key words: Vacuum-assisted closure therapy; povidone iodine; diabetic foot ulcer