Case Report
Year: 2016 | Month: November | Volume: 6 | Issue: 11 | Pages: 323-326
EBV Associated Diffuse Large B cell Lymphoma in a Child Mimicking Hodgkin Lymphoma - A Rare Case Report
Surekha Hemant Bhalekar1, Sonia Kundu2, Sunita Poriya3, Hemant Bhalekar4
1Associate Professor, Dept of Pathology, D. Y. Patil University School of Medicine,
Navi Mumbai, Maharashtra, India.
2Medical Officer, Civil Hospital, Panchkula, Haryana, India.
3Resident, Department of Pathology, M. P. Shah Government Medical College, Jamnagar, Gujarat, India.
4Pathologist, Dr Bhalekar Path Lab, New Panvel, Navi Mumbai, Maharashtra, India.
Corresponding Author: Sonia Kundu
ABSTRACT
Pediatric EBV+ DLBCL (Ebstain bar virus associated diffuse large B cell lymphoma) is a rare disease in non immunocompromised hosts of less than 10 years of age. This was a case of 6 years old boy having abdominal pain, fever, cervical and abdominal lymphadenopathy which on cytomorphology basis was diagnosed as Classical Hodgkin’s lymphoma, but latter was confirmed as EBV+DLBCL on histopathology and IHC ( immunohistochemistry). This report concluded that reactivation of EBV infection may lead to development of disease and EBV associated DLBCL affecting the paediatric patients had remarkable histologic, immunohistochemical, and molecular similarities to EBV+DLBCL of the elderly making the outcome comparable to the elderly counterpart.
Key words: Pediatric EBV+ DLBCL, EBV+DLBCL of the elderly, Lymphadenopathy, Classical Hodgkin’s Lymphoma, IHC (Immunohistochemistry).