Original Research Article
Year: 2016 | Month: October | Volume: 6 | Issue: 10 | Pages: 84-90
Derangement of Serum Electrolyte Status in Cerebrovascular Accident - A Hospital Based Observational Study in Shillong, Meghalaya
Meghna Borah1*, Kaustubh Bora1*, Dipankar M.Gogoi2**, Vinay Upadhyay1*, Alice A. Ruram3*, Happy Chutia4*
1SRD, 2PGT, 3Associate Professor and HOD in Charge, 4Assistant Professor,
*Department of Biochemistry, NEIGRIHMS.
**Department of Pharmacology, Assam Medical College and Hospital, Assam.
Corresponding Author: Alice A. Ruram
ABSTRACT
Background and Aim: The mortality rate of stroke patients with electrolyte imbalance has been found in previous studies to be higher than in patients with normal level. Hence the present study was carried out in a tertiary care hospital in Shillong, Meghalaya to assess the levels of serum electrolytes in patients admitted with Cerebrovascular accident (CVA).
Settings and design: A total of 164 participants (84 cases and 80 controls) were selected after careful screening, considering all relevant inclusion and exclusion criteria for the present hospital based observational case-control study. The serum samples were analyzed for electrolytes (sodium, potassium and chloride) on the same day of collection.
Results: A greater preponderance of CVA was seen in males as compared to females with a male: female ratio of 2.36:1. The levels of serum sodium and chloride in the cases were found to be higher than that in the controls, and the levels of serum potassium were found to be lower. This difference was statistically significant for all three parameters. Analysis by ANOVA between the three groups of cases found no significant difference in the levels of serum sodium and potassium. A significant difference was found in cases with chloride.
Conclusion: Prompt identification of such derangements along with their immediate correction can prove to be of tremendous importance in decreasing mortality as well as in dissipating the long term consequences of stroke. Further studies will be required to elucidate the role of serum electrolytes in CVA.
Key words: #Cerebrovascular accident, #Dyselectrolytemia, #Sodium, #Potassium, #Chloride, #North-East India.