Year: 2026 | Month: January | Volume: 16 | Issue: 1 | Pages: 213-226
DOI: https://doi.org/10.52403/ijhsr.20260126
Clinical Profile of Neonates on Bubble CPAP Ventilation in a Tertiary Care Centre
Dr Darshita Kothari1, Dr Sudhir S Sarawade2, Dr Neelam Belekar3, Dr Shraddha Khalate 4
1Junior Resident GMC, Kolhapur 2Professor and HOD GMC Kolhapur
3Assistant professor GMC Kolhapur 4Assistant professor GMC Kolhapur
Corresponding Author: Dr Darshita Kothari myname2tina@gmail.com
ABSTRACT
Background: Bubble-CPAP is an important, simple, non-invasive, and cost-effective treatment modality for respiratory distress in neonates. The present study was undertaken to study the clinical profile of neonates on bubble CPAP ventilation in a tertiary care centre.
Method: A total of 200 neonates were admitted in NICU with respiratory distress with Downe’s score 4-6 or Silverman Anderson scores -4-6 and Oxygen saturation SPO2 < 85% even with supplemental oxygen who require bubble CPAP ventilation were included in the study.
Results: The most common indication for B-CPAP was respiratory distress syndrome (RDS) (46%). B-CPAP was successful in 79% of neonates, with a 21% failure rate. There was a significant difference in B-CPAP failure rates based on specific indications. A significant association was found between comorbidities and B-CPAP failure. Neonates whose mothers received antenatal steroids had more successful B-CPAP outcomes. Neonates with successful B-CPAP outcomes required B-CPAP for a longer duration compared to those with treatment failure. Complication rates were significantly higher in neonates who experienced B-CPAP failure compared to those with successful B-CPAP outcomes. Most of the neonates experienced a positive outcome and survived (79%). However, among 42 neonates with B-CPAP failure, 6 died on B-CPAP, in 36 babies who were shifted to mechanical ventilation, 22 died on mechanical ventilation due to severe complications whereas 14 were recovered from mechanical ventilation.
Conclusion: B-CPAP is safe, effective, and easy to use in preterm and term neonates who require ventilation support. Also, bubble-CPAP is a much more cost-effective mode of ventilation as compared to mechanical ventilation.
Key words: Antenatal steroids; Bubble CPAP; Mechanical ventilation; Respiratory distress syndrome. .