Year: 2024 | Month: September | Volume: 14 | Issue: 9 | Pages: 225-231
DOI: https://doi.org/10.52403/ijhsr.20240929
Impact of Type 2 Diabetes Mellitus Duration on Sural Nerve Conduction Velocity: A Cross-Sectional Study
Lavkush Maurya1, Shraddha Singh1, S C Chaudhary1, Sudipti Yadav1, Pradeep Kumar Chauhan1, Pratibha Kushwaha1
1Department of Physiology, King George’s Medical University, Lucknow, India.
Corresponding Author: Dr. Lavkush Maurya
ABSTRACT
Objective: To evaluate the nerve conduction velocity (NCV) of the sural nerve in patients with Type 2 Diabetes Mellitus (T2DM) and compare it with healthy controls, focusing on the impact of the disease's duration on NCV.
Methods: This cross-sectional study included 90 T2DM patients divided into two groups based on disease duration (<5 years and >10 years) and 45 healthy controls. Sural nerve NCV was measured using an Octopus NCV/EMG/EP machine. Statistical analysis was performed using SPSS.
Results: The NCV of the sural nerve was significantly lower in T2DM patients compared to controls (p<0.001). NCV decreased significantly with increasing duration of diabetes, showing a reduction of approximately 1.80 m/s per year for the left sural nerve and 1.97 m/s per year for the right sural nerve.
Conclusions: Prolonged T2DM is associated with a significant reduction in sural nerve conduction velocity, indicating progressive nerve damage. Early diagnosis and management are crucial to prevent severe neuropathic complications.
Key words: Nerve Conduction Velocity, Sural Nerve, Type 2 Diabetes Mellitus, Diabetic Neuropathy