Year: 2024 | Month: September | Volume: 14 | Issue: 9 | Pages: 221-224
DOI: https://doi.org/10.52403/ijhsr.20240928
Triglyceride-Glucose Index: A Potential Indicator of Body Adiposity in Apparently Healthy Young Adults
Shivani Verma1, Sudipti Yadav1, Shraddha Singh2, Md Tanveer1, Archana Ghildiyal2
1Resident, Department of Physiology
2Professor, Department of Physiology
King George’s Medical University, Lucknow, India
Corresponding Author: Shivani Verma
ABSTRACT
INTRODUCTION: The increasing burden of obesity has become a major public health problem worldwide. According to recent studies, 650 million adults worldwide are obese and over 1.9 billion are overweight. More than 135 million people in India suffer from obesity. One essential part of the human body is adipose tissue. It serves as the primary energy store during times of dietary scarcity. Although it varies greatly among populations, total body fat (BF)typically accounts for 15% of men's and 25% of women's body weight. A sustained excess of calories consumed is generally accompanied by increased fat accumulation and leads to Insulin resistance. As a marker for insulin resistance (IR), the triglyceride-glucose index (TyG) can be easily computed through fasting measurements of plasm glucose and triglycerides, which are standard clinical laboratory tests. This study aims to find out the relationship of the triglyceride-glucose index with body fat percentage.
METHOD: The present study, which was a prospective analytical cross-sectional study, was carried out at the Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh over one year in apparently healthy young adults recruited from King George’s Medical University by setting up a health camp. After obtaining ethical approval and informed consent from the participants, a total of 128 participants were enrolled in the study using the inclusion and exclusion criteria. Individuals aged 18 to 45 years were included and individuals with a history of diabetes, hypertension, cardiovascular disease, renal disease, or any acute or visible illness were excluded.
RESULT: In the present study, the triglyceride-glucose index was found to have a strong positive correlation with body fat percentage (Spearman’s rho correlation coefficient=0.51, p < 0.01; Regression equation y=0.03x + 7.19, R square =0.24).
CONCLUSION: It can be concluded that the triglyceride-glucose index can be used as a potential indicator of body adiposity.
Key words: Triglyceride-Glucose Index, Adipose Tissue, Body Fat Percentage, Insulin Resistance.