Year: 2024 | Month: September | Volume: 14 | Issue: 9 | Pages: 45-54
DOI: https://doi.org/10.52403/ijhsr.20240906
A Prospective Observational Study on Evaluating the Appropriateness and Prescription Pattern of Restricted Antibiotics in a Quaternary Care Hospital
John Felix S.N1, Bala Krishnan P1, Deepak Hari S.S1, Vigneswaran R1, Guru Prasad Mohanta2, Vishnu T3
1Pharm D Intern Department of Pharmacy Practice, 2Professor and Head Department of Pharmacy Practice, 3Assistant Professor Department of Pharmacy Practice,
C. L. Baid Metha College of Pharmacy, Affiliated to “The Tamil Nadu Dr. M.G.R. Medical University”, Chennai, India.
Corresponding Author: John Felix S.N
ABSTRACT
Aim: To evaluate the appropriateness of Restricted Antibiotics in accordance with Indian Council of Medical Research (ICMR) guidelines and Prescription Pattern of Restricted Antibiotics in a quaternary care hospital.
Methodology: This prospective observational study included the in-patients of different wards in a quaternary care hospital who have been prescribed Restricted Antibiotics in the drug chart. The appropriateness of Restricted antibiotic use is assessed on the basis of the ICMR guidelines. The appropriateness of Restricted Antibiotics was verified, according to three main criteria: choice of antibiotic, dose, and frequency.
Results: A total of 110 patients who had been prescribed with Restricted Antibiotics were included in the study. The most prescribed Restricted Antibiotic was Meropenem (59.6 %) followed by Linezolid (18.5%). The overall appropriateness of Restricted Antibiotics was found to be 72.7%.
Conclusion: On evaluating the Prescription pattern of the Restricted Antibiotics, we concluded that Meropenem was the highly prescribed Restricted antibiotic in our hospital, followed by Linezolid, Levofloxacin, and Tigecycline. Even Though we conclude that most of the Antibiotics are prescribed appropriately, few patients were administered with inappropriate choice of Restricted Antibiotics. The findings also emphasized the significance of evaluating prescribing practices on a regular basis.
Key words: ICMR, Restricted Antibiotics, Prescription pattern