Year: 2024 | Month: October | Volume: 14 | Issue: 10 | Pages: 113-124
DOI: https://doi.org/10.52403/ijhsr.20241013
Exploring the Impact of Diet on Inflammation in Neurological Disorders: A Review
Sushma Swaraj Rapelly1, Shalini Suri2, Afreen Saif3, Nabila Nishat4
1Department of Physiology, 2Department of Physiology,
King George’s Medical College, Lucknow, India.
Corresponding Author: Sushma Swaraj Rapelly
ABSTRACT
Introduction: Neurological disorders pose significant challenges globally in terms of disability and mortality. Increasing evidence underscores the role of inflammatory processes and gut microbiome imbalances in these conditions, prompting exploration into dietary approaches like the Mediterranean, ketogenic diets, and DASH (Dietary Approaches to Stop Hypertension) for their potential benefits. With ongoing advancements in understanding neurodegenerative diseases like Alzheimer’s, Parkinson’s, Multiple sclerosis, Depression, and Schizophrenia, there is a heightened focus on finding more impactful interventions.
Methods: This review delves into the influence of diet and its components on inflammation linked to neurological diseases like Alzheimer’s disease development and progression. Data from in vitro experiments, animal models, and various studies are integrated, providing a comprehensive analysis of effectiveness of nutritional interventions to combat neurodegenerative disorders. Systematic searches of reputable databases like PubMed and Google Scholar ensured the inclusion of up-to-date and reliable literature.
Key Findings: Data suggests that adopting a diet rich in anti-inflammatory elements such as minerals, vitamins, polyphenols, omega-3 fatty acids and probiotics from vegetables, fruits, spices, herbs, nuts, and legumes could foster a brain-friendly environment and reduce neurological disease risks.
Conclusion: Nutritional strategies hold promises as a non-invasive and effective approach to combatting these disorders.
Key words: Neurological conditions, inflammation, anti-inflammatory diet, Nutrition intervention, psychological disorders, Degenerative brain disorders, Alzheimer’s Disease