Original Research Article
Year: 2023 | Month: February | Volume: 13 | Issue: 2 | Pages: 210-216
DOI: https://doi.org/10.52403/ijhsr.20230229
D-Dimer Levels in Covid-19 Patients with Moderate and Severe Symptoms
Erida Manalu1,2, Jonathan Josafat1, Danny Ernest Jonas Luhulima1,2
1Medical Faculty, Universitas Kristen Indonesia, Jakarta, Indonesia
2UKI General Hospital, Jakarta, Indonesia
Corresponding Author: Erida Manalu
ABSTRACT
COVID-19 is an infectious disease in humans. This disease is caused by a new virus similar to SARS-CoV, called SARS-CoV-2. This virus attacks the human respiratory system and causes symptoms such as cough, fever above 38°C, shortness of breath, muscle aches, malaise, and diarrhea. Elevated levels of D-Dimer are often found in patients with severe COVID-19 symptoms. Previous studies have shown that increased levels of D-Dimer can increase the risk of death and is also a marker of poor prognosis. The purpose of this study was to provide an overview of D-Dimer levels in patients confirmed by COVID-19 with moderate and severe symptoms at UKI General Hospital. This study is a cross-sectional study with descriptive and analytic data presentation from the Medical Record document of UKI General Hospital. Data that has been collected was processed using the Mann-Whitney test. The subjects of this study are 211 patients who were confirmed to have COVID-19 through RT-PCR examination and had checked for D-Dimer levels. The Mann-Whitney test that was carried out gave a p-value <0.05, which means a significant difference in the mean D-Dimer level between COVID-19 patients with moderate and severe symptoms. The average level of D-Dimer in moderate symptoms was 441.272 ng/mL with 154 patients. The average level of D-Dimer in severe symptoms is 1,231,630 ng/mL with 57 patients.
Key words: D-Dimer, COVID-19, mild symptoms, severe symptoms.