Case Report
Year: 2023 | Month: January | Volume: 13 | Issue: 1 | Pages: 90-96
DOI: https://doi.org/10.52403/ijhsr.20230112
Actinomycetoma Treated with Oral Trimethoprim + Sulfamethoxazole and Amoxicillin with Clavulanic Acid: A Case Report
Pooja Shrivastava1, Manjunatha P2
1Junior Resident, Department of Dermatology, Venereology, Leprosy, KVG Medical College and Hospital, Sullia, India
2Professor, Department of Dermatology, Venereology, Leprosy, KVG Medical College and Hospital, Sullia, India
Corresponding Author: Pooja Shrivastava
ABSTRACT
Mycetoma is endemic in many developing countries. We report here a case of actinomycetoma in a 60 year old male, farmer by occupation, patient gave history of bare foot walking and patient recalls history of trivial trauma over legs who presented with diffuse multiple plaques studded with discharging sinuses and surrounding oedema over the medial aspect of left ankle. Patient is a known case of uncontrolled T2DM on insulin and altered renal parameters that posed as a therapeutic challenge where welsh/modified welsh regimen could not be planned in this patient.
Based on clinical and histological picture and Pus & culture sensitivity reports patient was treated with oral Sulfamethoxazole 800mg with Trimethoprim 160mg two tablets daily and oral amoxicillin with clavulanic acid 1gm twice daily for 4months showed marked improvement, lesions dried up after four months and healed with post inflammatory hyperpigmentation & scars.
This case is presented to demonstrate how early disease diagnosis and prompt treatment can reduce the significant morbidity associated with this devastating infection.
Key words: Actinomycetoma, Suppurative granuloma, Trimethoprim-sulfamethoxazole (SMX+TMP), Amoxicillin clavulanic acid