Year: 2023 | Month: October | Volume: 13 | Issue: 10 | Pages: 8-20
DOI: https://doi.org/10.52403/ijhsr.20231002
A Study to Observe the Clinical and Angiographic Profile of Diabetic and Nondiabetic Acute Coronary Syndrome (ACS) Patients Admitted in the Department of Cardiology of a Tertiary Care Hospital in Kolkata
Supratip Kundu1, Bappaditya Kumar2, Somnath Mukhopadhay3
1Department of Cardiology, AMRI Hospital, Dhakuria, Kolkata, India
2,3Department of Cardiology, AMRI Hospital, Salt Lake, Kolkata, India
Corresponding Author: Bappaditya Kumar
ABSTRACT
Background: A large body of literature documents that diabetes is an independent risk factor for cardiovascular diseases (CVD) in both men and women. Diabetic female seem to lose their inherent protections against developing CVD. CVDs are listed as the cause of death in 65% of persons with diabetes. Not only coronary artery diseases (CAD), diabetes acts as an independent risk factor for several other forms of CVD. Moreover, patients with diabetes have worse prognosis compared to their nondiabetic counterpart.
Aims & Objectives:
The aim of this study was-
To observe clinical and angiographic profile of diabetic and nondiabetic acute coronary syndrome (ACS) patients
To observe the difference between baseline characteristics, clinical profile and angiographic profile of these patients
Methods:
Study Area: Department of Cardiology, Tertiary Care Hospital in Kolkata
Study Population: Patient diagnosed as a case of acute coronary syndrome and admitted to cardiology ward of the Hospital.
SAMPLE SIZE: 637 consecutive patients, admitted to department of cardiology were selected for this study
Results: About one third patients in our study were diabetic. Compared to non-diabetic, these diabetic patients were older. Women patients were more in case of diabetic. STEMI and UA as presentation was more common amongst diabetic female. Prognosis of female ACS were also bad compared to their male counterpart. Hypertension, Dyslipidemia in the form hypertriglyceridemia, renal insufficiency was significantly more common among diabetics whereas smoking and family history of premature CAD were more common in nondiabetic patients. Atypical manifestation was more common among diabetic population which might be the reason of delayed presentation among diabetic patients. Less number of diabetic patients presented within the time period of thrombolysis. Compared to nondiabetic, diabetic patients had higher in hospital mortality, cardiogenic shock or heart failure. Higher in-hospital mortality could be predicted by higher admission hyperglycemia. Double and triple vessel disease were more common among diabetic patients. higher the HBA1c value, more was the chance of triple vessel involvement. Left main involvement was more common in diabetic population, however chronic total occlusion rates were same.
Key words: ACS, CVD, Diabetes