Original Research Article
Year: 2022 | Month: May | Volume: 12 | Issue: 5 | Pages: 238-250
DOI: https://doi.org/10.52403/ijhsr.20220525
Physicochemical Evaluation and Standardization of Siddha Formulation Ratthi Naagara Rasa Mezhugu by Modern Techniques
J Kumar1, S Heamavathi2, M D Saravana Devi3, V Velpandian4
1Post Graduate Scholar, Post Graduate Department Gunapadam, Government Siddha Medical College, Chennai,
2Post Graduate Scholar, Post Graduate Department Gunapadam, Government Siddha Medical College, Chennai;
3Head of the Department Professor, Post Graduate Department of Gunapadam,
Government Siddha Medical College, Arumbakkam, Chennai,
4Professor, Post Graduate Department of Gunapadam, Government Siddha Medical College, Arumbakkam, Chennai
Corresponding Author: J. Kumar
ABSTRACT
Siddha medicine has own idiosyncratic way to treat various diseases. The Siddha system has different formulation in herbal, mineral, poly-herbal, herbo-mineral. Ratthi Naagara Rasa Mezhugu is a herbo-mineral formulation mentioned in the Siddha literature which indicated for Rheumatoid arthritis, penile cancer, vaginal cancer. The present study indicates the quality of the drug Ratthinaagara rasa mezhugu identified by physicochemical analysis, phytochemical analysis and organoleptic characters and other analytical techniques was based on the PLIM guidelines. High-performance thin-layer chromatography finger printing was done through CAMAG software. Physicochemical analysis of this drug was done such as Loss on drying at 105ºC was 15.2 ± 0.7211%, Total Ash value was 0.47±0.1323%, Acid insoluble Ash valve was 0.036±0.015%, Water soluble Extractive value was 4.9±0.5292%, Alcohol soluble extractive value was 11.37±1.097% and PH value was 4. The phytochemical analysis results in the presence of alkaloid, steroid, phenols. The drug RRM was free from microbial contamination; the heavy metal analysis and pesticide residues below quantification limit. The results indicate the drug is of standard quality and can be used as reference standard in laying pharmacopoeia standard.
Key words: Siddha, Physicochemical analysis, Standardization, RatthiNaagara Rasa Mezhugu, PLIM guidelines.