Original Research Article
Year: 2021 | Month: July | Volume: 11 | Issue: 7 | Pages: 81-88
DOI: https://doi.org/10.52403/ijhsr.20210712
The Effect of the Decoction of Citrus aurantifolia (Lime) and Camellia sinensis (Lipton Tea) on the Plasma Glucose; Plasma Total Protein, Albumin Concentrations and Weight of Normal Albino Rats
Ojoye Preiye1, Tawari Erebi Patricia1, Boloya Vukumo Eric1, Kasia Benedicta Erere1, Prohp The Prophet2
1Department of Chemical Pathology, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Bayelsa State, Nigeria.
2Department of Biochemistry, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Bayelsa State, Nigeria.
Corresponding Author: Tawari Erebi Patricia
ABSTRACT
Citrus aurantifolia is one of the major fruit trees that grow throughout the world and it’s known for its refreshing juice and health benefits. Some attributes of citrus aurantifolia (lime) include pharmacological properties (antitumor anti-inflammatory, anti-cancer). This study was aimed at determining the effects of the decoction of citrus aurantifolia and camellia sinensis (Lipton tea) on the glucose, plasma total protein and plasma albumin concentration in normal albino rats. Twenty-four (24) female healthy albino rats of Wister strain aged 3weeks and with an average of weight of 150g were randomly placed into two [2] groups of twelve rats each (control and test) after acclimatization for one week. The lime and Lipton tea was administered orally to the test group for 14days. Blood samples were collected from each rats and analyzed spectrophotometrically for plasma glucose, total protein and albumin. The liver, heart and kidney tissues were collected also for histological studies. Analysis of result shows that the plasma glucose decreased significantly (p<0.05) and the histological report showed that the liver and the kidneys were affected adversely but had no effect on the heart; the plasma total protein decreased significantly (p<0.05) and had adverse affection on the liver and kidneys. There was no significant increase in plasma albumin [p>0.05], however histological report showed effect on the liver and kidneys. In conclusion the lime and Lipton tea can be clinically significant in the reduction of high plasma glucose levels in the management of diabetes mellitus, treatment of obesity due to its protein reducing ability and has effect on plasma albumin; however, concentrations and doses administered could have adverse effect on the liver and kidneys.
Key words: Lime, Lipton tea, Glucose, Total protein, Albumin, Albino rats.