Original Research Article
Year: 2020 | Month: January | Volume: 10 | Issue: 1 | Pages: 82-87
Comparison of Antiurolithiatic Property of Orthosiphon spiralis, Hedychium marginatum, Thunbergia alata and Cystone: A Herbal Drug
O. Ibopishak Singh, A. Bimola Devi
Associate Professor, Chemistry Department, Modern College (affiliated to MU, Canchipur), Imphal East - 795005, Manipur, India
Corresponding Author: O.Ibopishak Singh
ABSTRACT
Kidney is one of the vital parts of the human body. Malfunction of kidney is due to blockage of stone in the urinary tract and urinary infection. Peoples are mainly focused on the treatment of kidney stone by using medicinal plants. Patients suffering from kidney stone may be treated by Lithotripsy, Ureteroscopy, open or Laparoscopy. Such treatment is costly and painful. Now-a- days medicinal plants are mainly used for such treatment because these plants are less side effect and more economic. In the present study, the inhibitory potency of crude extracts of Orthosiphon spiralis, Hedychium marginatum and Thunbergia alata in methanol were evaluated on the formation of calcium phosphate(CP) and on the growth of calcium oxalate monohydrate(COM) crystals in vitro. Also, comparison of antiurolithiatic property of these plants and Cystone, a herbal drug, is studied. Results show that Cystone is effective in the inhibition of CP stone both in aqueous and urinary media while Orthosiphon spiralis has the highest inhibitory effect for COM both in aqueous and urinary media in vitro.
Key words: Lithotripsy, Kidney stone, Herbal drug, Inhibition, Antilithiatic, Ureteroscopy